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Symbol
Name
ID
Pla2g2d
phospholipase A2, group IID
MGI:1341796
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal dendritic cell migration
increased dendritic cell number
increased CD4-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
decreased leukocyte cell number
abnormal effector T cell morphology
abnormal cytotoxic T cell physiology
abnormal dendritic cell physiology
increased susceptibility to type IV hypersensitivity reaction
increased interferon-gamma secretion
decreased interleukin-6 secretion
decreased tumor necrosis factor secretion
decreased susceptibility to Coronaviridae infection induced morbidity/mortality
decreased susceptibility to Coronaviridae infection
Availability Mouse Genotype
Pla2g2dtm1.1(KOMP)Vlcg/Pla2g2dtm1.1(KOMP)Vlcg
Pla2g2dtm1.1Mhg/Pla2g2dtm1.1Mhg *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory